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Identification of novel psychoactive substances (NPS) based on comparisons of electron-ionization (EI) mass spectra continues to pose challenges in seized drug analysis. In this webinar, a method to statistically compare EI mass spectra is described, and an application of the method to distinguish several structural and positional isomers of NPS analogs are demonstrated.

This webinar was hosted by the NIJ Forensic Technology Center of Excellence on July 25, 2024. 

Of recent, forensic toxicology laboratories have been grappling with the emergence of tetrahydrocannabinol isomers within biological specimens. Traditional methodologies are often inadequate in the separation of Δ9-tetrahydrocannabinol and Δ8-tetrahydrocannabinol, which are the most common isomers identified in forensic testing.